Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDCR372849
| Cat. No. | CDCR372849 |
| Product Type | ORF Clone |
| Gene Abbr | Loxl2 |
| Species | Rat |
| Tag | C-terminal Myc-DDK |
| ORF Size | 2331 bp |
| Vector | pCMV6-Entry |
| Target Gene | LOXL2 |
| Background | This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008] |
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