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Rat Kcna2 cDNA Clone(NM_012970.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010778

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Gene Information

Cat. No. CDFR010778
Description NativeORF clone of Rattus norvegicus potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2) as transfection-ready DNA NM_012970.3
Product Type cDAN Clone
Gene Abbr Kcna2
Species Rat
Vector pCMV6Entry
Target Gene KCNA2
Background Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. [provided by RefSeq, Jul 2008]
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