Transfected Stable Cell Lines
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Cat. No. : CDCL184833
| Cat. No. | CDCL184833 |
| Description | ORF Clone of Rattus norvegicus interleukin 1 receptor antagonist DNA. |
| Product Type | ORF clone |
| Gene Abbr | IL1RN |
| Species | Rat |
| ORF Size | 537bp |
| Vector | pMD18-T |
| Warning | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Storage | store at -20°C |
| Target Gene | IL1RN |
| Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020] |
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