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Rat IL1RN ORF clone(NM_022194.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL184833

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Product Information

Gene Information

Cat. No. CDCL184833
Description ORF Clone of Rattus norvegicus interleukin 1 receptor antagonist DNA.
Product Type ORF clone
Gene Abbr IL1RN
Species Rat
ORF Size 537bp
Vector pMD18-T
Warning This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage store at -20°C
Target Gene IL1RN
Background The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020]
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