Transfected Stable Cell Lines
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Cat. No. : CDCR372372
| Cat. No. | CDCR372372 |
| Product Type | ORF Clone |
| Gene Abbr | Havcr2 |
| Species | Rat |
| Tag | C-terminal Myc-DDK |
| ORF Size | 849 bp |
| Vector | pCMV6-Entry |
| Target Gene | HAVCR2 |
| Background | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011] |
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