Transfected Stable Cell Lines
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Cat. No. : CDCL184039
| Cat. No. | CDCL184039 |
| Description | ORF Clone of Rattus norvegicus endoglin DNA. |
| Product Type | ORF clone |
| Gene Abbr | ENG |
| Species | Rat |
| ORF Size | 1953bp |
| Vector | pGEM-T |
| Warning | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Storage | store at -20°C |
| Target Gene | ENG |
| Background | This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013] |
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