Human ENG HEK293 Cell Lysate

Name: Human ENG HEK293 Cell Lysate
SKU: CLOE-1685
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1685 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1685
Introduction	This cell lysate over-expresses the human ENG (NP_001108225.1) (Met 1-Gly 586) fused with the Fc region of human IgG1 at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	ENG
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	ENG endoglin [ Homo sapiens ]
Gene Symbol	ENG
Synonyms	END; ORW; HHT1; ORW1; CD105
Gene Description	endoglin (Osler-Rendu-Weber syndrome 1)
GeneID	2022
Uni ProtID	P17813
mRNA Refseq	NM_000118.2
Protein Refseq	NP_000109.1
Chromosome Location	9q34.11
Function	activin binding; galactose binding; glycosaminoglycan binding; glycosaminoglycan binding; protein binding; contributes_to protein binding; protein homodimerization activity; protein homodimerization activity; transforming growth factor beta binding; transforming growth factor beta receptor, cytoplasmic mediator activity; transforming growth factor beta-activated receptor activity; transmembrane signaling receptor activity; type I transforming growth factor beta receptor binding; type I transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding;
Pathway	HIF-1-alpha transcription factor network, organism-specific biosystem; TGF Beta Signaling Pathway, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem;
MIM	131195

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