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Rat Dmd cDNA Clone(NM_001005244.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001443

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Gene Information

Cat. No. CDFR001443
Description NativeORF clone of Rattus norvegicus dystrophin, muscular dystrophy (Dmd), transcript variant Dp71ab as transfection-ready DNA NM_001005244.1
Product Type cDAN Clone
Gene Abbr Dmd
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene DMD
Background This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
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