shRNA set against Human DMD (NM_000109.3)

Name: shRNA set against Human DMD (NM_000109.3)
SKU: SHH278785
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH278785

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Product Information

Gene Information

Cat. No.	SHH278785
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	DMD
Gene Name	DMD dystrophin [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	DMD dystrophin [ Homo sapiens ]
Gene Symbol	DMD
Synonyms	BMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Gene Description	dystrophin (muscular dystrophy, Duchenne and Becker types)
GeneID	1756
Uni ProtID	P11532
mRNA Refseq	NM_004019.2
Protein Refseq	NP_004010.1
Chromosome Location	Xp21.2
Function	actin binding; dystroglycan binding; nitric-oxide synthase binding; protein binding; structural constituent of cytoskeleton; structural constituent of muscle; structural constituent of muscle; zinc ion binding;
Pathway	Arrhythmogenic right ventricular cardiomyopathy, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; Hypertrophic cardiomyopathy (HCM), conserved biosystem;
MIM	300377

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