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Rat Dmd ORF Clone(NM_012698.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR377559

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Gene Information

Cat. No. CDCR377559
Product Type ORF Clone
Gene Abbr Dmd
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1815 bp
Vector pCMV6-Entry
Target Gene DMD
Background This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
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