Pages
Products

Rat Cldn18 cDNA Clone(NM_001014096.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003227

Inquire for Price

Product Information

Gene Information

Cat. No. CDFR003227
Description NativeORF clone of Rattus norvegicus claudin 18 (Cldn18) as transfection-ready DNA NM_001014096.1
Product Type cDAN Clone
Gene Abbr Cldn18
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene CLDN18
Background This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction