Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR014828
| Cat. No. | CDFR014828 |
| Description | NativeORF clone of Rattus norvegicus Bcl-2 binding component 3 (Bbc3) as transfection-ready DNA NM_173837.2 |
| Product Type | cDAN Clone |
| Gene Abbr | Bbc3 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | BBC3 |
| Background | This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011] |
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