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Rat Bbc3 ORF Clone(NM_173837.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR381915

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Product Information

Gene Information

Cat. No. CDCR381915
Product Type ORF Clone
Gene Abbr Bbc3
Species Rat
Tag C-terminal Myc-DDK
ORF Size 582 bp
Vector pCMV6-Entry
Target Gene BBC3
Background This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
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