Panoply™ Human BBC3 Knockdown Stable Cell Line

Name: Panoply™ Human BBC3 Knockdown Stable Cell Line
SKU: CSC-DC001337
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC001337

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC001337
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	BBC3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	BBC3 BCL2 binding component 3 [ Homo sapiens ]
Gene Symbol	BBC3
Synonyms	JFY1; PUMA; JFY-1
Gene ID	27113
Uni Prot ID	Q96PG8
m RNA Refseq	NM_001127240.2
Protein Refseq	NP_001120712.1
Chromosome Location	19q13.3-q13.4
Function	protein binding;
Pathway	Activation of BH3-only proteins, organism-specific biosystem; Activation of PUMA and translocation to mitochondria, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis Modulation and Signaling, organism-specific biosystem; BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members, organism-specific biosystem; DNA damage response, organism-specific biosystem;
MIM	605854

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