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Panoply™ Human TREX1 Knockdown Stable Cell Line

Cat.No.
CSC-DC016554
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
TREX1
Synonyms
TREX1; three prime repair exonuclease 1; AGS1, Aicardi Goutieres syndrome 1; DRN3; DNase III; 3 repair exonuclease 1; 3-5 exonuclease TREX1; CRV; AGS1; HERNS; DKFZp434J0310;
Gene ID
UniProt ID
Q9NSU2
mRNA Refseq
BC023630
Chromosome Location
3p21.31
Function
3-5 exonuclease activity; 3-5 exonuclease activity; 3-5-exodeoxyribonuclease activity; MutLalpha complex binding; MutSalpha complex binding; adenyl deoxyribonucleotide binding; double-stranded DNA binding; exodeoxyribonuclease III activity; hydrolase activity; metal ion binding; metal ion binding; nucleic acid binding; protein homodimerization activity; protein homodimerization activity; single-stranded DNA binding;
Pathway
Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem;
MIM

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