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TREX1

Official Full Name
three prime repair exonuclease 1
Organism
Homo sapiens
GeneID
11277
Background
This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
Synonyms
CRV; AGS1; DRN3; HERNS; RVCLS;

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