Panoply™ Human POR Over-expressing Stable Cell Line

Name: Panoply™ Human POR Over-expressing Stable Cell Line
SKU: CSC-SC012134
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC012134

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC012134
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	POR
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	POR P450 (cytochrome) oxidoreductase [ Homo sapiens ]
Gene Symbol	POR
Synonyms	CPR; CYPOR; P450R
Gene Description	P450 (cytochrome) oxidoreductase
GeneID	5447
Uni ProtID	P16435
mRNA Refseq	NM_000941.2
Protein Refseq	NP_000932.3
Chromosome Location	7q11.2
Function	FMN binding; NADP binding; NADPH-hemoprotein reductase activity; NADPH-hemoprotein reductase activity; cytochrome-b5 reductase activity; electron carrier activity; enzyme binding; flavin adenine dinucleotide binding; hydrolase activity; iron ion binding; iron-cytochrome-c reductase activity; protein binding;
Pathway	1,25-dihydroxyvitamin D3 biosynthesis, organism-specific biosystem; 1,25-dihydroxyvitamin D3 biosynthesis, conserved biosystem; bile acid biosynthesis, neutral pathway, organism-specific biosystem; bile acid biosynthesis, neutral pathway, conserved biosystem; cytochrome P450, organism-specific biosystem; melatonin degradation I, organism-specific biosystem; melatonin degradation I, conserved biosystem;
MIM	124015

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