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Panoply™ Human POR Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC012134

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC012134
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene POR
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name POR P450 (cytochrome) oxidoreductase [ Homo sapiens ]
Gene Symbol POR
Synonyms CPR; CYPOR; P450R
Gene Description P450 (cytochrome) oxidoreductase
GeneID 5447
Uni ProtID P16435
mRNA Refseq NM_000941.2
Protein Refseq NP_000932.3
Chromosome Location 7q11.2
Function FMN binding; NADP binding; NADPH-hemoprotein reductase activity; NADPH-hemoprotein reductase activity; cytochrome-b5 reductase activity; electron carrier activity; enzyme binding; flavin adenine dinucleotide binding; hydrolase activity; iron ion binding; iron-cytochrome-c reductase activity; protein binding;
Pathway 1,25-dihydroxyvitamin D3 biosynthesis, organism-specific biosystem; 1,25-dihydroxyvitamin D3 biosynthesis, conserved biosystem; bile acid biosynthesis, neutral pathway, organism-specific biosystem; bile acid biosynthesis, neutral pathway, conserved biosystem; cytochrome P450, organism-specific biosystem; melatonin degradation I, organism-specific biosystem; melatonin degradation I, conserved biosystem;
MIM 124015
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