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POR


Official Full Name
cytochrome p450 oxidoreductase
Organism
Homo sapiens
Gene ID
5447
Background
This gene encodes an endoplasmic reticulum membrane oxidoreductase that is essential for multiple metabolic processes, including reactions catalyzed by cytochrome P450 proteins for metabolism of steroid hormones, drugs and xenobiotics. The encoded protein has a flavin adenine dinucleotide (FAD)-binding domain and a flavodoxin-like domain which bind two cofactors, FAD and FMN, that allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene cause a complex set of disorders, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome, that resemble those caused by defects in steroid metabolizing enzymes such as aromatase, 21-hydroxylase, and 17 alpha-hydroxylase. [provided by RefSeq, Aug 2020]
Synonyms
CPR; CYPOR; P450R

Cat.No. Product Name Price
LV22262L human POR (NM_000941) lentivirus particles Inquiry
Cat.No. Product Name Price
SHW009343 shRNA set against Danio rerio POR (NM_001034982) Inquiry
SHH379884 shRNA set against Human POR (NM_000941.2) Inquiry
SHH379888 shRNA set against Mouse POR (NM_008898.1) Inquiry
SHH379892 shRNA set against Rat POR (NM_031576.1) Inquiry
SHR129390 shRNA set against Mouse Por(NM_008898.1) Inquiry
SHR129408 shRNA set against Human POR(NM_000941.2) Inquiry
SHR129480 shRNA set against Rat Por(NM_031576.1) Inquiry
SHW003099 shRNA set against Chicken POR (NM_001195796) Inquiry
Cat.No. Product Name Price
CDCR379767 Rat Por ORF Clone(NM_031576.1) Inquiry
CDFH014737 Human POR cDNA Clone(NM_000941.2) Inquiry
CDFR012734 Rat Por cDNA Clone(NM_031576.1) Inquiry
MiUTR1H-08101 POR miRNA 3'UTR clone Inquiry
MiUTR1M-09426 POR miRNA 3'UTR clone Inquiry
MiUTR1R-05969 POR miRNA 3'UTR clone Inquiry
SKO0686 POR Validated sgRNA vector Inquiry
CDCB164574 Chicken POR ORF Clone (NM_001195796) Inquiry
CDCB170818 Danio rerio POR ORF Clone (NM_001034982) Inquiry
CDCB180408 Rabbit POR ORF clone (NM_001160290.1) Inquiry
CDCH066154 Mouse Por ORF clone (NM_008898.1) Inquiry
CDCL185772 Human POR ORF clone(NM_000941.2) Inquiry
CDCS406006 Human POR ORF Clone (BC034277) Inquiry
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