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Panoply™ Human NPC1L1 Knockdown Stable Cell Line

Cat.No.
CSC-DC010541
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
NPC1L1
Synonyms
NPC11L1
Gene Description
NPC1 (Niemann-Pick disease, type C1, gene)-like 1
Gene ID
UniProt ID
D3DVK9
mRNA Refseq
Protein Refseq
Chromosome Location
7p13
Function
Rab GTPase binding; hedgehog receptor activity; myosin V binding; protein binding;
Pathway
Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Trafficking of dietary sterols, organism-specific biosystem; Vitamin A and carotenoid metabolism, organism-specific biosystem;
MIM

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