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Panoply™ Human ITCH Knockdown Stable Cell Line

Cat.No.
CSC-DC007779
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ITCH
Synonyms
AIF4; AIP4; NAPP1; dJ468O1.1
Gene ID
UniProt ID
Q96J02
mRNA Refseq
Protein Refseq
Chromosome Location
20q11.22
Function
CXCR chemokine receptor binding; protein binding; ribonucleoprotein complex binding; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity;
Pathway
Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Class I MHC mediated antigen processing &
MIM

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