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ITCH


Official Full Name
itchy E3 ubiquitin protein ligase
Organism
Homo sapiens
Gene ID
83737
Background
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
Synonyms
AIF4; AIP4; ADMFD; NAPP1

Cat.No. Product Name Price
SHH321081 shRNA set against Mouse ITCH (NM_008395.3) Inquiry
SHH321077 shRNA set against Human ITCH (NM_031483.5) Inquiry
SHH321085 shRNA set against Rat ITCH (NM_001005887.1) Inquiry
SHL174918 shRNA set against Rat Itch(NM_001005887.1) Inquiry
SHW014277 shRNA set against Danio rerio ITCHA (NM_001287095) Inquiry
SHW014366 shRNA set against Danio rerio ITCH (NM_001302226) Inquiry
Cat.No. Product Name Price
CDFG022265 Mouse Itch cDNA Clone(BC062934) Inquiry
CDFR001326 Rat Itch cDNA Clone(NM_001005887.1) Inquiry
MiUTR1R-02704 ITCH miRNA 3'UTR clone Inquiry
CDCB175752 Danio rerio ITCHA ORF Clone (NM_001287095) Inquiry
CDCB175841 Danio rerio ITCH ORF Clone (NM_001302226) Inquiry
CDCB183906 Rabbit ITCH ORF clone (XM_008256089.1) Inquiry
CDCL121823 Human ITCH ORF clone (NM_001257138.1) Inquiry
CDCR368567 Rat Itch ORF Clone(NM_001005887.1) Inquiry
Cat.No. Product Name Price
CC-706 ITCH Easy KO Kit Inquiry
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