Panoply™ Human CDK2 Over-expressing Stable Cell Line

Name: Panoply™ Human CDK2 Over-expressing Stable Cell Line
SKU: CSC-SC002869
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-SC002869

Host Cell : HEK293 (CHO and other cell types are also available) Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-SC002869
Description	Using Creative Biogene's proprietary lentiviral vectors, we subclone the target gene into lentivector, generate the lentivirus particles, sequentially infect the cell line HEK293 (other cell types are also available according to your requirements), and select the clones constantly expressing target gene at high level.
Target Gene	CDK2
Gene Species	Homo sapiens (Human)
Host Cell	HEK293 (CHO and other cell types are also available)
Host Cell Species	Species varies
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Disease research
Size	2 × 10^6 cells / vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry Ice

Revival

Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CDK2 cyclin-dependent kinase 2 [ Homo sapiens ]
Gene Symbol	CDK2
Synonyms	p33(CDK2)
Gene Description	cyclin-dependent kinase 2
GeneID	1017
Uni ProtID	P24941
mRNA Refseq	NM_001798.3
Protein Refseq	NP_001789.2
Chromosome Location	12q13
Function	ATP binding; cyclin binding; cyclin-dependent protein kinase activity; cyclin-dependent protein kinase activity; contributes_to histone kinase activity; metal ion binding; protein binding; protein kinase activity;
Pathway	APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; Activation of ATR in response to replication stress, organism-specific biosystem; Activation of the pre-replicative complex, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; CDK-mediated phosphorylation and removal of Cdc6, organism-specific biosystem; Cell Cycle, organism-specific biosystem;
MIM	116953

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