Panoply™ Human CDK2 Knockdown Stable Cell Line

Name: Panoply™ Human CDK2 Knockdown Stable Cell Line
SKU: CSC-DC002869

Cat.No. : CSC-DC002869

Host Cell: HEK293 (Hela and other cell types are also available) Validation: Real-Time RCR

Inquire for Price

Cell Line Information

Safety and Packaging

Cat. No.	CSC-DC002869
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Gene	CDK2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Stability	Validated for at least 10 passages
Application	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Size Form	>1 × 10^6 cells / vial
Shipping	Dry Ice
Storage	Liquid Nitrogen

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Quick Inquiry

Publications

Q & A

Customer Reviews

Customer Q&As

What is CDK？

A: CDKs, or cyclin-dependent kinases, are a set of Ser/Thr kinase systems that correspond to the cell cycle progression.

What is the role of CDK?

A: Various CDKs are activated alternately along the cell cycle chronotope to phosphorylate the corresponding substrates and keep the cell cycle events in order.

What is the role of cyclin-dependent protein kinase?

A: Cyclin-dependent protein kinases, a group of serine/threonine protein kinases, CDK drives the cell cycle through chemotaxis on serine/threonine proteins and, in synergy with cyclin, is an important factor in cell cycle regulation.

How does CDK work in the cell?

A: CDK can bind to cyclin to form a heterodimer, where CDK is the catalytic subunit and cyclin is the regulatory subunit. Different cyclin-CDK complexes, through CDK activity, catalyze the phosphorylation of different substrates, while achieving the advancement and transformation of different phases of the cell cycle.

The activity of CDK depends on the regulation of what substance?

A: CDK activity depends on the sequential expression of its positive regulatory subunit cyclin and the concentration of its negative regulatory subunit CKI (cyclin dependent kinase inhibitor, CDK inhibitor). Also, CDK activity is regulated by phosphorylation and dephosphorylation, as well as by oncogenes and oncogenes.

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

First Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *