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MSH2 miRNA 3'UTR clone

For research use only. Not intended for any clinical use.

Cat. No. :   MiUTR3H-10534

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Gene Information

Cat. No. MiUTR3H-10534
Description 3'UTR clone of mutS homolog 2 colon cancer nonpolyposis type 1 (E. coli) (MSH2) for miRNA target validation
Gene Abbr MSH2
Gene Name MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) [ Homo sapiens ]
Species Human
Reporter luciferase-RFP
Promoter SV40
Resistance Neo/Kanr
Selection Marker Neomycin
Size The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
Vector pMirTarget
Vector Type plasmid
Storage -20 ℃
Gene Name MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) [ Homo sapiens ]
Gene Symbol MSH2
Synonyms MSH2; mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli); COCA1, mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1); DNA mismatch repair protein Msh2; HNPCC; HNPCC1; hMSH2; FCC1; COCA1; LCFS2;
Gene ID 4436
Uni Prot ID P43246
m RNA Refseq BC021566
Chromosome Location 2p21
Function contributes_to ADP binding; contributes_to ATP binding; contributes_to ATPase activity; DNA binding; DNA-dependent ATPase activity; contributes_to MutLalpha complex binding; Y-form DNA binding; centromeric DNA binding; damaged DNA binding; contributes_to dinucleotide insertion or deletion binding; contributes_to dinucleotide repeat insertion binding; double-strand/single-strand DNA junction binding; contributes_to double-stranded DNA binding; enzyme binding; contributes_to four-way junction DNA binding; contributes_to guanine/thymine mispair binding; guanine/thymine mispair binding; loop DNA binding; contributes_to magnesium ion binding; contributes_to mismatched DNA binding; nucleotide binding; contributes_to oxidized purine DNA binding; protein C-terminus binding; protein binding; contributes_to protein binding; protein homodimerization activity; protein kinase binding; contributes_to single guanine insertion binding; contributes_to single thymine insertion binding; contributes_to single-stranded DNA binding;
Pathway BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; Colorectal cancer, organism-specific biosystem; Colorectal cancer, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Mismatch repair, organism-specific biosystem; Mismatch repair, conserved biosystem; Pathways in cancer, organism-specific biosystem;
MIM 609309
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