Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : MiUTR3H-10534
| Cat. No. | MiUTR3H-10534 |
| Description | 3'UTR clone of mutS homolog 2 colon cancer nonpolyposis type 1 (E. coli) (MSH2) for miRNA target validation |
| Gene Abbr | MSH2 |
| Gene Name | MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) [ Homo sapiens ] |
| Species | Human |
| Reporter | luciferase-RFP |
| Promoter | SV40 |
| Resistance | Neo/Kanr |
| Selection Marker | Neomycin |
| Size | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
| Vector | pMirTarget |
| Vector Type | plasmid |
| Storage | -20 ℃ |
| Gene Name | MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) [ Homo sapiens ] |
| Gene Symbol | MSH2 |
| Synonyms | MSH2; mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli); COCA1, mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1); DNA mismatch repair protein Msh2; HNPCC; HNPCC1; hMSH2; FCC1; COCA1; LCFS2; |
| Gene ID | 4436 |
| Uni Prot ID | P43246 |
| m RNA Refseq | BC021566 |
| Chromosome Location | 2p21 |
| Function | contributes_to ADP binding; contributes_to ATP binding; contributes_to ATPase activity; DNA binding; DNA-dependent ATPase activity; contributes_to MutLalpha complex binding; Y-form DNA binding; centromeric DNA binding; damaged DNA binding; contributes_to dinucleotide insertion or deletion binding; contributes_to dinucleotide repeat insertion binding; double-strand/single-strand DNA junction binding; contributes_to double-stranded DNA binding; enzyme binding; contributes_to four-way junction DNA binding; contributes_to guanine/thymine mispair binding; guanine/thymine mispair binding; loop DNA binding; contributes_to magnesium ion binding; contributes_to mismatched DNA binding; nucleotide binding; contributes_to oxidized purine DNA binding; protein C-terminus binding; protein binding; contributes_to protein binding; protein homodimerization activity; protein kinase binding; contributes_to single guanine insertion binding; contributes_to single thymine insertion binding; contributes_to single-stranded DNA binding; |
| Pathway | BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; Colorectal cancer, organism-specific biosystem; Colorectal cancer, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Mismatch repair, organism-specific biosystem; Mismatch repair, conserved biosystem; Pathways in cancer, organism-specific biosystem; |
| MIM | 609309 |
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