Human MSH2 ORF clone (BC021566)

Name: Human MSH2 ORF clone (BC021566)
SKU: CDCB158951
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For research use only. Not intended for any clinical use.

Cat. No. : CDCB158951

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Gene Information

Cat. No.	CDCB158951
Description	ORF Clone of Homo sapiens mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) DNA. Identical with the Gene Bank Ref.ID sequence.
Gene Abbr	MSH2
Gene Name	MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) [ Homo sapiens ]
Species	Human
ORF Size	2805 bp
Sequence	ATGGCGGTGC AGCCGAAGGA GACGCTGCAG TTGGAGAGCG CGGCCGAGGT CGGCTTCGTG CGCTTCTTTC AGGGCATGCC GGAGAAGCCG ACCACCACAG TGCGCCTTTT CGACCGGGGC GACTTCTATA CGGCGCACGG CGAGGACGCG CTGCTGGCCG CCCGGGAGGT GTTCAAGACC CAGGGGGTGA TCAAGTACAT GGGGCCGGCA GGAGCAAAGA ATCTGCAGAG TGTTGTGCTT AGTAAAATGA ATTTTGAATC TTTTGTAAAA GATCTTCTTC TGGTTCGTCA GTATAGAGTT GAAGTTTATA AGAATAGAGC TGGAAATAAG GCATCCAAGG AGAATGATTG GTATTTGGCA TATAAGGCTT CTCCTGGCAA TCTCTCTCAG TTTGAAGACA TTCTCTTTGG TAACAATGAT ATGTCAGCTT CCATTGGTGT TGTGGGTGTT AAAATGTCCG CAGTTGATGG CCAGAGACAG GTTGGAGTTG GGTATGTGGA TTCCATACAG AGGAAACTAG GACTGTGTGA ATTCCCTGAT AATGATCAGT TCTCCAATCT TGAGGCTCTC CTCATCCAGA TTGGACCAAA GGAATGTGTT TTACCCGGAG GAGAGACTGC TGGAGACATG GGGAAACTGA GACAGATAAT TCAAAGAGGA GGAATTCTGA TCACAGAAAG AAAAAAAGCT GACTTTTCCA CAAAAGACAT TTATCAGGAC CTCAACCGGT TGTTGAAAGG CAAAAAGGGA GAGCAGATGA ATAGTGCTGT ATTGCCAGAA ATGGAGAATC AGGTTGCAGT TTCATCACTG TCTGCGGTAA TCAAGTTTTT AGAACTCTTA TCAGATGATT CCAACTTTGG ACAGTTTGAA CTGACTACTT TTGACTTCAG CCAGTATATG AAATTGGATA TTGCAGCAGT CAGAGCCCTT AACCTTTTTC AGGGTTCTGT TGAAGATACC ACTGGCTCTC AGTCTCTGGC TGCCTTGCTG AATAAGTGTA AAACCCCTCA AGGACAAAGA CTTGTTAACC AGTGGATTAA GCAGCCTCTC ATGGATAAGA ACAGAATAGA GGAGAGATTG AATTTAGTGG AAGCTTTTGT AGAAGATGCA GAATTGAGGC AGACTTTACA AGAAGATTTA CTTCGTCGAT TCCCAGATCT TAACCGACTT GCCAAGAAGT TTCAAAGACA AGCAGCAAAC TTACAAGATT GTTACCGACT CTATCAGGGT ATAAATCAAC TACCTAATGT TATACAGGCT CTGGAAAAAC ATGAAGGAAA ACACCAGAAA TTATTGTTGG CAGTTTTTGT GACTCCTCTT ACTGATCTTC GTTCTGACTT CTCCAAGTTT CAGGAAATGA TAGAAACAAC TTTAGATATG GATCAGGTGG AAAACCATGA ATTCCTTGTA AAACCTTCAT TTGATCCTAA TCTCAGTGAA TTAAGAGAAA TAATGAATGA CTTGGAAAAG AAGATGCAGT CAACATTAAT AAGTGCAGCC AGAGATCTTG GCTTGGACCC TGGCAAACAG ATTAAACTGG ATTCCAGTGC ACAGTTTGGA TATTACTTTC GTGTAACCTG TAAGGAAGAA AAAGTCCTTC GTAACAATAA AAACTTTAGT ACTGTAGATA TCCAGAAGAA TGGTGTTAAA TTTACCAACA GCAAATTGAC TTCTTTAAAT GAAGAGTATA CCAAAAATAA AACAGAATAT GAAGAAGCCC AGGATGCCAT TGTTAAAGAA ATTGTCAATA TTTCTTCAGG CTATGTAGAA CCAATGCAGA CACTCAATGA TGTGTTAGCT CAGCTAGATG CTGTTGTCAG CTTTGCTCAC GTGTCAAATG GAGCACCTGT TCCATATGTA CGACCAGCCA TTTTGGAGAA AGGACAAGGA AGAATTATAT TAAAAGCATC CAGGCATGCT TGTGTTGAAG TTCAAGATGA AATTGCATTT ATTCCTAATG ACGTATACTT TGAAAAAGAT AAACAGATGT TCCACATCAT TACTGGCCCC AATATGGGAG GTAAATCAAC ATATATTCGA CAAACTGGGG TGATAGTACT CATGGCCCAA ATTGGGTGTT TTGTGCCATG TGAGTCAGCA GAAGTGTCCA TTGTGGACTG CATCTTAGCC CGAGTAGGGG CTGGTGACAG TCAATTGAAA GGAGTCTCCA CGTTCATGGC TGAAATGTTG GAAACTGCTT CTATCCTCAG GTCTGCAACC AAAGATTCAT TAATAATCAT AGATGAATTG GGAAGAGGAA CTTCTACCTA CGATGGATTT GGGTTAGCAT GGGCTATATC AGAATACATT GCAACAAAGA TTGGTGCTTT TTGCATGTTT GCAACCCATT TTCATGAACT TACTGCCTTG GCCAATCAGA TACCAACTGT TAATAATCTA CATGTCACAG CACTCACCAC TGAAGAGACC TTAACTATGC TTTATCAGGT GAAGAAAGGT GTCTGTGATC AAAGTTTTGG GATTCATGTT GCAGAGCTTG CTAATTTCCC TAAGCATGTA ATAGAGTGTG CTAAACAGAA AGCCCTGGAA CTTGAGGAGT TTCAGTATAT TGGAGAATCG CAAGGATATG ATATCATGGA ACCAGCAGCA AAGAAGTGCT ATCTGGAAAG AGAGCAAGGT GAAAAAATTA TTCAGGAGTT CCTGTCCAAG GTGAAACAAA TGCCCTTTAC TGAAATGTCA GAA

Gene Name	MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) [ Homo sapiens ]
Gene Symbol	MSH2
Synonyms	MSH2; mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli); COCA1, mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1); DNA mismatch repair protein Msh2; HNPCC; HNPCC1; hMSH2; FCC1; COCA1; LCFS2;
Gene ID	4436
Uni Prot ID	P43246
m RNA Refseq	BC021566
Chromosome Location	2p21
Function	contributes_to ADP binding; contributes_to ATP binding; contributes_to ATPase activity; DNA binding; DNA-dependent ATPase activity; contributes_to MutLalpha complex binding; Y-form DNA binding; centromeric DNA binding; damaged DNA binding; contributes_to dinucleotide insertion or deletion binding; contributes_to dinucleotide repeat insertion binding; double-strand/single-strand DNA junction binding; contributes_to double-stranded DNA binding; enzyme binding; contributes_to four-way junction DNA binding; contributes_to guanine/thymine mispair binding; guanine/thymine mispair binding; loop DNA binding; contributes_to magnesium ion binding; contributes_to mismatched DNA binding; nucleotide binding; contributes_to oxidized purine DNA binding; protein C-terminus binding; protein binding; contributes_to protein binding; protein homodimerization activity; protein kinase binding; contributes_to single guanine insertion binding; contributes_to single thymine insertion binding; contributes_to single-stranded DNA binding;
Pathway	BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; Colorectal cancer, organism-specific biosystem; Colorectal cancer, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Mismatch repair, organism-specific biosystem; Mismatch repair, conserved biosystem; Pathways in cancer, organism-specific biosystem;
MIM	609309

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