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Human MSH2 Knockdown Cell Line-LN428 Glioma

Cat.No.
CSC-RK0231
Abbr
LN428 Glioma-HuMSH2 Knockdown
Alias
MSH2,HNPCC,HNPCC1,hMSH2,FCC1,COCA1,LCFS2,
Growth Properties
Adherent
Host Cell
LN428 glioma
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

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