Luciferase Reporter Stable Cell Line - SK-OV-3

Luciferase is the general term for a class of oxidative enzymes that produce bioluminescence. It is extracted from fluorescein, and with the help of oxygen, it undergoes a series of reactions that cause it to glow. Luciferase is the basis of scientific research in various fields, especially in the field of genetics, where it is often used as a reporter gene to examine the activity of other genes. Luciferase reporter genes are paired with target signaling pathways or specific gene promoters to indicate the activity of the target pathway or gene expression through luminescence levels. The luminescence signal is easy to measure, greatly aiding researchers in drug screening applications or exploring gene function.

The luciferase reporter stable cell line-SKOV-3 has the luciferase gene exogenously integrated into the SKOV-3 cell genome. SKOV-3 is a human ovarian cancer cell line first isolated in 1973 from the malignant ascites of a 64-year-old white woman with ovarian adenocarcinoma. SK-OV-3 cells are commonly used in cancer research to study ovarian cancer biology, drug resistance mechanisms and explore potential therapeutic targets. The luciferase reporter stable cell line-SKOV-3 is a reliable tool to study the activity of specific genes or signaling pathways and provides a powerful platform for drug screening applications.