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Human XLF Knockdown Cell Line-HeLa

Cat.No.
CSC-RK0020
Abbr
HeLa-HuXLF Knockdown
Alias
NHEJ1,Cernunnos,FLJ12610,XLF,
Growth Properties
Adherent
Host Cell
HeLa
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.

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