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Human XLF Knockdown Cell Line-HeLa

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Cat.No.
CSC-RK0020
Background
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HeLa
Ship
Dry ice
Gene Information
Official Symbol
NHEJ1
Synonyms
NHEJ1; nonhomologous end-joining factor 1; non-homologous end-joining factor 1; Cernunnos; FLJ12610; XLF; XRCC4-like factor; protein cernunnos;
Gene ID
MIM
UniProt ID
Q9H9Q4
Chromosome Location
2q35
Pathway
Non-homologous end joining, organism-specific biosystem; Non-homologous end-joining, organism-specific biosystem; Non-homologous end-joining, conserved biosystem;
Function
DNA binding; protein binding;

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