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NHEJ1

Official Full Name
non-homologous end joining factor 1
Organism
Homo sapiens
GeneID
79840
Background
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008]
Synonyms
XLF; IMD124; MCOPCB13;

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