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Human STK11 lentiviral particles

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Cat.No.
LV00076Z
Product name
Human STK11 lentiviral particle
Description
STK11/LKB1 gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11/LKB1 gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder chara
Insert
STK11
Species
Human
Type
Lentiviral particle
titer
0.9 x 10^8 TU/ml
Product Size
9.0ml
Storage
Store at -20 centigrade
Antigen Gene Information
Official Symbol
STK11
Synonyms
STK11; serine/threonine kinase 11; serine/threonine kinase 11 (Peutz Jeghers syndrome); serine/threonine-protein kinase STK11; LKB1; PJS; polarization related protein LKB1; liver kinase B1; polarization-related protein LKB1; renal carcinoma antigen NY-REN
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q15831
Chromosome Location
19p13.3
Pathway
AMPK inhibits chREBP transcriptional activation activity, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Energy dependent regulation of mTOR by LKB1-AMPK, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem;
Function
ATP binding; LRR domain binding; magnesium ion binding; nucleotide binding; p53 binding; protein binding; protein kinase activator activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity;

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