Human SCARB1 lentiviral particles

Name: Human SCARB1 lentiviral particles
SKU: LV00456Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : LV00456Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	LV00456Z
Description	Human SCARB1 ORF cDNA is cloned into the lentiviral expression vector for maximal stable delivery. The ready-to-use lentiviruses accelerate experiments investigating exogenous gene overexpression phenotypes and downstream molecular impacts.
Product Type	Lentiviral particle
Gene	SCARB1
Species	Human
Titer	Varies lot by lot, for example, ≥110^7 TU/mL, ≥110^8 TU/mL, ≥1*10^9 TU/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality lentivirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between lentivirus particle lots.
Mycoplasma	Creative Biogene routinely tests for mycoplasma contamination using a mycoplasma detection kit. Cell lines are maintained for approximately 20 passages before being discarded and replaced with a new vial of early passage cells. Approximately 2 weeks after thawing, cell culture supernatants are tested for mycoplasma contamination. Creative Biogene ensures that lentiviral products are free of mycoplasma contamination.
Purity	Creative Biogene evaluates the level of impurities, such as residual host cell DNA or proteins, in prepared lentiviral vectors to ensure they meet quality standards.
Sterility	The lentiviral samples were inoculated into cell culture medium for about 5 days and the growth of bacteria and fungi was tested. Creative Biogene ensures that the lentiviral products are free of microbial contamination.
Transducibility	Upon requirement, Creative Biogene can perform in vitro or in vivo transduction assays to evaluate the ability of lentivirus to deliver genetic material into target cells, and assess gene expression and functional activities.
Proviral Identity Confirmation	All Creative Biogene lentiviral vectors are confirmed to have correctly integrated provirus using PCR. This test involves transducing cells with serial dilutions of the lentiviral vector, harvesting the cells a few days later, and isolating genomic DNA. This DNA is then used as a template to amplify a portion of the expected lentiviral insert.

Gene Name	SCARB1 scavenger receptor class B, member 1 [ Homo sapiens ]
Gene Symbol	SCARB1
Synonyms	CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6
Gene Description	scavenger receptor class B, member 1
Gene ID	949
Uni Prot ID	F8W8N0
m RNA Refseq	NM_001082959.1
Protein Refseq	NP_001076428.1
Chromosome Location	12q24.31
Function	1-phosphatidylinositol binding; apolipoprotein A-I binding; apolipoprotein binding; high-density lipoprotein particle binding; high-density lipoprotein particle receptor activity; lipopolysaccharide binding; lipopolysaccharide receptor activity; low-density lipoprotein particle binding; phosphatidylserine binding; protein homodimerization activity; transporter activity;
Pathway	Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Folate Metabolism, organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem; Hepatitis C, organism-specific biosystem;
MIM	601040

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