Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : AD09710Z
Storage : -80℃ Shipping : Frozen on dry ice
Titer: Size:
| Cat. No. | AD09710Z |
| Description | Adenovirus with ORF of methyl-CpG binding domain protein 2 (MBD2), transcript variant 2. |
| Gene | MBD2 |
| Species | Human |
| Titer | Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc. |
| Size | Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc. |
| Storage | Store at -80℃. Avoid multiple freeze/thaw cycles. |
| Shipping | Frozen on dry ice |
| Summary | Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots. |
| Endotoxin | Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance. |
| Sterility | Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination. |
| Ad5 E1 Detection | All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination. |
| RCA Assays | Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources. |
| PFU Titering | All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells. |
| Gene Name | MBD2 methyl-CpG binding domain protein 2 [ Homo sapiens ] |
| Gene Symbol | MBD2 |
| Synonyms | DMTase; NY-CO-41 |
| Gene ID | 8932 |
| Uni Prot ID | Q9UBB5 |
| m RNA Refseq | NM_015832.4 |
| Protein Refseq | NP_056647.1 |
| Chromosome Location | 18q21 |
| Function | C2H2 zinc finger domain binding; chromatin binding; mRNA binding; methyl-CpG binding; methyl-CpG binding; protein binding; protein domain specific binding; satellite DNA binding; siRNA binding; |
| Pathway | Gene Expression, organism-specific biosystem; RNA Polymerase I Promoter Clearance, organism-specific biosystem; RNA Polymerase I Promoter Opening, organism-specific biosystem; RNA Polymerase I Transcription, organism-specific biosystem; RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, organism-specific biosystem; Signaling events mediated by HDAC Class I, organism-specific biosystem; |
| MIM | 603547 |
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