Human MAP3K11 adenoviral particles

Name: Human MAP3K11 adenoviral particles
SKU: AD09621Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD09621Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD09621Z
Description	Adenovirus with ORF of mitogen-activated protein kinase kinase kinase 11 (MAP3K11).
Gene	MAP3K11
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	MAP3K11 mitogen-activated protein kinase kinase kinase 11 [ Homo sapiens ]
Gene Symbol	MAP3K11
Synonyms	MLK3; PTK1; SPRK; MLK-3; MEKK11
Gene Description	mitogen-activated protein kinase kinase kinase 11
GeneID	4296
Uni ProtID	Q16584
mRNA Refseq	NM_002419.3
Protein Refseq	NP_002410.1
Chromosome Location	11q13.1-q13.3
Function	ATP binding; JUN kinase kinase kinase activity; Rac GTPase binding; identical protein binding; mitogen-activated protein kinase kinase binding; mitogen-activated protein kinase kinase kinase binding; protein binding; protein homodimerization activity; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity;
Pathway	CDC42 signaling events, organism-specific biosystem; IFN-gamma pathway, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; RAC1 signaling pathway, organism-specific biosystem;
MIM	600050

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