Panoply™ Human MAP3K11 Knockdown Stable Cell Line

Name: Panoply™ Human MAP3K11 Knockdown Stable Cell Line
SKU: CSC-DC009167
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC009167

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC009167
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	MAP3K11
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	MAP3K11 mitogen-activated protein kinase kinase kinase 11 [ Homo sapiens ]
Gene Symbol	MAP3K11
Synonyms	MLK3; PTK1; SPRK; MLK-3; MEKK11
Gene Description	mitogen-activated protein kinase kinase kinase 11
GeneID	4296
Uni ProtID	Q16584
mRNA Refseq	NM_002419.3
Protein Refseq	NP_002410.1
Chromosome Location	11q13.1-q13.3
Function	ATP binding; JUN kinase kinase kinase activity; Rac GTPase binding; identical protein binding; mitogen-activated protein kinase kinase binding; mitogen-activated protein kinase kinase kinase binding; protein binding; protein homodimerization activity; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity;
Pathway	CDC42 signaling events, organism-specific biosystem; IFN-gamma pathway, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; RAC1 signaling pathway, organism-specific biosystem;
MIM	600050

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