Human GRIN2B ORF clone (NM_000834.3)

Name: Human GRIN2B ORF clone (NM_000834.3)
SKU: CDCL114737
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL114737

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Product Information

Gene Information

Cat. No.	CDCL114737
Description	Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B), mRNA.
Product Type	ORF clone
Gene Abbr	GRIN2B
Gene Name	GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B [ Homo sapiens ]
Species	Human
ORF Size	4455bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Gene Name	GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B [ Homo sapiens ]
Gene Symbol	GRIN2B
Synonyms	MRD6; NR2B; hNR3; GluN2B; NMDAR2B
Gene Description	glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GeneID	2904
Uni ProtID	Q13224
mRNA Refseq	NM_000834.3
Protein Refseq	NP_000825.2
Chromosome Location	12p12
Function	D2 dopamine receptor binding; N-methyl-D-aspartate selective glutamate receptor activity; beta-catenin binding; calcium channel activity; cell adhesion molecule binding; drug binding; extracellular-glutamate-gated ion channel activity; glycine binding; ionotropic glutamate receptor binding; neurotransmitter binding; protein binding; protein heterodimerization activity; zinc ion binding;
Pathway	Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem;
MIM	138252

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