Human BMPR1A adenoviral particles

Name: Human BMPR1A adenoviral particles
SKU: AD01862Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD01862Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD01862Z
Description	Adenovirus with ORF of bone morphogenetic protein receptor, type IA (BMPR1A).
Gene	BMPR1A
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	BMPR1A bone morphogenetic protein receptor, type IA [ Homo sapiens ]
Gene Symbol	BMPR1A
Synonyms	ALK3; SKR5; CD292; ACVRLK3; 10q23del
Gene Description	bone morphogenetic protein receptor, type IA
GeneID	657
Uni ProtID	P36894
mRNA Refseq	NM_004329.2
Protein Refseq	NP_004320.2
Chromosome Location	10q22.3
Function	ATP binding; SMAD binding; metal ion binding; protein binding; protein homodimerization activity; protein serine/threonine kinase activity; sequence-specific DNA binding RNA polymerase II transcription factor activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity;
Pathway	BMP signalling and regulation, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endochondral Ossification, organism-specific biosystem; Heart Development, organism-specific biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
MIM	601299

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