Panoply™ Human BMPR1A Knockdown Stable Cell Line

Name: Panoply™ Human BMPR1A Knockdown Stable Cell Line
SKU: CSC-DC001480
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC001480

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC001480
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	BMPR1A
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	BMPR1A bone morphogenetic protein receptor, type IA [ Homo sapiens ]
Gene Symbol	BMPR1A
Synonyms	ALK3; SKR5; CD292; ACVRLK3; 10q23del
Gene Description	bone morphogenetic protein receptor, type IA
GeneID	657
Uni ProtID	P36894
mRNA Refseq	NM_004329.2
Protein Refseq	NP_004320.2
Chromosome Location	10q22.3
Function	ATP binding; SMAD binding; metal ion binding; protein binding; protein homodimerization activity; protein serine/threonine kinase activity; sequence-specific DNA binding RNA polymerase II transcription factor activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity;
Pathway	BMP signalling and regulation, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endochondral Ossification, organism-specific biosystem; Heart Development, organism-specific biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
MIM	601299

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