Human BMPR1A HEK293 Cell Lysate

Name: Human BMPR1A HEK293 Cell Lysate
SKU: CLOE-1407
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-1407 Host Cell : HEK293

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-1407
Introduction	This cell lysate over-expresses the human BMPR1A (NP_004320.2) (Met 1-Arg 152) fused with a polyhistidine tag and the Fc region of human IgG1 at the C-terminus. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	BMPR1A
Host Cell	HEK293
Host Cell Species	Homo sapiens (Human)
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Growth Properties	Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO₂. Split at 80-90% confluence, approximately 1:3-1:6.
Media Type	Cells were cultured in DMEM supplemented with 10% fetal bovine serum.
Freeze Medium	Complete medium supplemented with 10% (v/v) DMSO
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Gene Name	BMPR1A bone morphogenetic protein receptor, type IA [ Homo sapiens ]
Gene Symbol	BMPR1A
Synonyms	ALK3; SKR5; CD292; ACVRLK3; 10q23del
Gene Description	bone morphogenetic protein receptor, type IA
GeneID	657
Uni ProtID	P36894
mRNA Refseq	NM_004329.2
Protein Refseq	NP_004320.2
Chromosome Location	10q22.3
Function	ATP binding; SMAD binding; metal ion binding; protein binding; protein homodimerization activity; protein serine/threonine kinase activity; sequence-specific DNA binding RNA polymerase II transcription factor activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity;
Pathway	BMP signalling and regulation, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endochondral Ossification, organism-specific biosystem; Heart Development, organism-specific biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
MIM	601299

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