Human AKAP13 adenoviral particles

Name: Human AKAP13 adenoviral particles
SKU: AD00841Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD00841Z

Storage : -80℃ Shipping : Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD00841Z
Description	Adenovirus with ORF of A kinase (PRKA) anchor protein 13 (AKAP13), transcript variant 3.
Gene	AKAP13
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	AKAP13 A kinase (PRKA) anchor protein 13 [ Homo sapiens ]
Gene Symbol	AKAP13
Synonyms	AKAP13; A kinase (PRKA) anchor protein 13; LBC, lymphoid blast crisis oncogene; A-kinase anchor protein 13; AKAP Lbc; ARHGEF13; BRX; c lbc; HA 3; Ht31; PROTO LB; p47; AKAP-13; LBC oncogene; A-kinase anchoring protein; lymphoid blast crisis oncogene; human thyroid-anchoring protein 31; protein kinase A-anchoring protein 13; guanine nucleotide exchange factor Lbc; non-oncogenic Rho GTPase-specific GTP exchange factor; breast cancer nuclear receptor-binding auxiliary protein; LBC; HA-3; c-lbc; PRKA13; AKAP-Lbc; PROTO-LB; PROTO-LBC; FLJ11952; FLJ43341;
Gene ID	11214
Uni Prot ID	Q12802
m RNA Refseq	BC050312
Chromosome Location	15q24-q25
Pathway	Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; G Protein Signaling Pathways, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; Regulation of RhoA activity, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem;
MIM	604686

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