Pages
Products

Rat Akap13 cDNA Clone(NM_001106271.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006027

Inquire for Price

Product Information

Gene Information

Cat. No. CDFR006027
Description NativeORF clone of Rattus norvegicus A kinase (PRKA) anchor protein 13 (Akap13) as transfection-ready DNA NM_001106271.2
Product Type cDAN Clone
Gene Abbr Akap13
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene AKAP13
Background The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction