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BCL2 miRNA 3'UTR clone

For research use only. Not intended for any clinical use.

Cat. No. :   MiUTR1H-00840

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Gene Information

Cat. No. MiUTR1H-00840
Description miRNA 3′UTR target expression clone for Human NM_000657.2
Gene Abbr BCL2
Gene Name BCL2 B-cell CLL/lymphoma 2 [ Homo sapiens ]
Species Human
Reporter GLuc-SEAP
Promoter Sv40
Resistance Amp
Selection Marker Neomycin
Size 10 μg purified plasmid
Vector pEZX-MT05
Vector Type plasmid
Storage -20 ℃
Gene Name BCL2 B-cell CLL/lymphoma 2 [ Homo sapiens ]
Gene Symbol BCL2
Synonyms Bcl-2; PPP1R50
GeneID 596
Uni ProtID P10415
mRNA Refseq NM_000633.2
Protein Refseq NP_000624.2
Chromosome Location 18q21.3
Function BH3 domain binding; channel activity; identical protein binding; protease binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein phosphatase 2A binding; sequence-specific DNA binding; transcription factor binding; ubiquitin protein ligase binding;
Pathway ATF-2 transcription factor network, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem;
MIM 151430
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Publications

  1. Tao S, Gu J, Wang Q, et al. Translational control of Bcl-2 promotes apoptosis of gastric carcinoma cells[J]. BMC cancer, 2021, 21(1): 1-10.
  2. Zhou Z, You Z. Mesenchymal stem cells alleviate LPS-induced acute lung injury in mice by MiR-142a-5p-controlled pulmonary endothelial cell autophagy[J]. Cellular Physiology and Biochemistry, 2016, 38(1): 258-266.
  3. Bao H, Gao F, Xie G, et al. Angiotensin-converting enzyme 2 inhibits apoptosis of pulmonary endothelial cells during acute lung injury through suppressing MiR-4262[J]. Cellular Physiology and Biochemistry, 2015, 37(2): 759-767.
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