shRNA set against Rat BCL2 (NM_016993.1)

Name: shRNA set against Rat BCL2 (NM_016993.1)
SKU: SHH245890
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH245890

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Product Information

Gene Information

Cat. No.	SHH245890
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	BCL2
Gene Name	Bcl2 B cell leukemia/lymphoma 2 [ Mus musculus ]
Species	Rat
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Bcl2 B cell leukemia/lymphoma 2 [ Mus musculus ]
Gene Symbol	BCL2
Synonyms	Bcl-2; AW986256; C430015F12Rik; D630044D05Rik; D830018M01Rik
GeneID	12043
Uni ProtID	Q6NTH7
mRNA Refseq	NM_177410.2
Protein Refseq	NP_803129.2
Chromosome Location	1 E2.1; 1 59.8 cM
Function	BH domain binding; BH3 domain binding; channel activity; identical protein binding; protease binding; protein binding; protein heterodimerization activity; protein heterodimerization activity; protein homodimerization activity; protein phosphatase 2A binding; protein phosphatase binding; transcription factor binding; ubiquitin protein ligase binding;
Pathway	Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis signaling pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members, organism-specific biosystem; Cholinergic synapse, organism-specific biosystem; Colorectal cancer, organism-specific biosystem; Colorectal cancer, conserved biosystem; Epstein-Barr virus infection, organism-specific biosystem; Epstein-Barr virus infection, conserved biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; HIF-1 signaling pathway, organism-specific biosystem; Hepatitis B, organism-specific biosystem; IL-2 Signaling Pathway, organism-specific biosystem; IL-3 Signaling Pathway, organism-specific biosystem; Immune System, organism-specific biosystem; Inflammasomes, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Intrinsic Pathway for Apoptosis, organism-specific biosystem; NF-kappa B signaling pathway, organism-specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem; Neurotrophin signaling pathway, conserved biosystem; Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, organism-specific biosystem; Oxidative Damage, organism-specific biosystem; PI3K-Akt signaling pathway, organism-specific biosystem; PI3K-Akt signaling pathway, conserved biosystem; Pathways in cancer, organism-specific biosystem; Prostate cancer, organism-specific biosystem; Prostate cancer, conserved biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem; Small cell lung cancer, organism-specific biosystem; Small cell lung cancer, conserved biosystem; The NLRP1 inflammasome, organism-specific biosystem; Toxoplasmosis, organism-specific biosystem; Toxoplasmosis, conserved biosystem; Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem; estrogen signalling, organism-specific biosystem;

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