Transfected Stable Cell Lines
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Cat. No. : VNV-016
| Cat. No. | VNV-016 |
| Description | Wild type human metapneumovirus 9 (hMPV, type A1) which are inactivated by heat treatment. This product is intended for research use only. |
| Storage | -80°C |
| Shipping | Dry ice |
A: When comparing the wild-type hMPV 9 A1 strain to other strains of hMPV, there may be variations in various aspects such as the genetic sequence, antigenic properties, and clinical presentations. These differences can lead to distinct characteristics and behaviors of the virus.
A: Wild-type hMPV 9 A1 exhibits certain characteristics that make it suitable for research purposes. Firstly, it possesses a single-stranded RNA genome that can be easily manipulated in the laboratory to study its replication and genetic variations. Secondly, hMPV 9 A1 is highly contagious, allowing researchers to study its transmission dynamics and the development of antiviral strategies. Additionally, this strain has been well-characterized and extensively studied, providing a solid foundation for further investigations into its pathogenesis, immune response, and vaccine development. These attributes make wild-type hMPV 9 A1 a promising model for research aimed at understanding and combating respiratory viral infections.
A: The genome of Human Metapneumovirus (HMPV) is a single-stranded, negative-sense RNA molecule and is organized into three main sections: the 3' leader sequence, the gene region, and the 5' trailer sequence.
A: HMPV is thought to attach to target cells through glycoprotein (G) interactions with heparan sulfate and other glycosaminoglycans. The HMPV fusion (F) protein encodes an RGD (Arg-Gly-Asp) motif that engages RGD-binding integrins as cellular receptors, then mediates fusion of the cell membrane and viral envelope in a pH-independent fashion, likely within endosomes.
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This virus shows excellent infectivity, replicates efficiently, and accurately mimics the natural infection process.
The company's commitment to quality control ensures consistent performance, and their rigorous production methods give me confidence in the product's reliability.
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