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shRNA set against Rat TOP1 (NM_022615.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH432844

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Gene Information

Cat. No. SHH432844
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr TOP1
Gene Name Top1 topoisomerase (DNA) I [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Top1 topoisomerase (DNA) I [ Mus musculus ]
Gene Symbol Top1
Synonyms Top-1; AI467334; D130064I21Rik
Gene Description topoisomerase (DNA) I
Gene ID 21969
Uni Prot ID Q04750
m RNA Refseq NM_009408.2
Protein Refseq NP_033434.2
Chromosome Location 2 H2-3; 2 92.0 cM
Function ATP binding; DNA binding; DNA topoisomerase (ATP-hydrolyzing) activity; DNA topoisomerase activity; DNA topoisomerase type I activity; DNA topoisomerase type I activity; chromatin DNA binding; chromatin binding; isomerase activity; nucleotide binding; protein complex binding;
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