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Panoply™ Human TOP1 Knockdown Stable Cell Line

Cat.No.
CSC-DC016432
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
TOP1
Synonyms
TOPI
Gene Description
topoisomerase (DNA) I
Gene ID
UniProt ID
P11387
mRNA Refseq
Protein Refseq
Chromosome Location
20q12-q13.1
Function
ATP binding; DNA binding; DNA topoisomerase (ATP-hydrolyzing) activity; DNA topoisomerase type I activity; chromatin binding; protein binding;
Pathway
Caspase cascade in apoptosis, organism-specific biosystem; Integrated Pancreatic Cancer Pathway, organism-specific biosystem;
MIM

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