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shRNA set against Rat PTGS2 (NM_017232.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH386156

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Gene Information

Cat. No. SHH386156
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr PTGS2
Gene Name Ptgs2 prostaglandin-endoperoxide synthase 2 [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Ptgs2 prostaglandin-endoperoxide synthase 2 [ Mus musculus ]
Gene Symbol Ptgs2
Synonyms COX2; Cox-2; PHS-2; Pghs2; TIS10; PGHS-2
Gene Description prostaglandin-endoperoxide synthase 2
GeneID 19225
Uni ProtID Q05769
mRNA Refseq NM_011198.3
Protein Refseq NP_035328.2
Chromosome Location 1 H1; 1 76.2 cM
Function enzyme binding; heme binding; lipid binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; peroxidase activity; prostaglandin-endoperoxide synthase activity; prostaglandin-endoperoxide synthase activity; protein homodimerization activity;
Pathway Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Arachidonic acid metabolism pathway, organism-specific biosystem; Arachidonic acid metabolism via COX (Cyclooxygenase) pathway, organism-specific biosystem; Chemical carcinogenesis, organism-specific biosystem; Chemical carcinogenesis, conserved biosystem;
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