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shRNA set against Rat PDE4B (NM_017031.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH372448

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Gene Information

Cat. No. SHH372448
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr PDE4B
Gene Name Pde4b phosphodiesterase 4B, cAMP specific [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Pde4b phosphodiesterase 4B, cAMP specific [ Mus musculus ]
Gene Symbol Pde4b
Synonyms Dpde4; dunce; R74983
Gene Description phosphodiesterase 4B, cAMP specific
GeneID 18578
Uni ProtID Q8VBU5
mRNA Refseq NM_019840.2
Protein Refseq NP_062814.2
Chromosome Location 4 C6; 4 46.8 cM
Function 3,5-cyclic-AMP phosphodiesterase activity; 3,5-cyclic-AMP phosphodiesterase activity; hydrolase activity; metal ion binding;
Pathway DARPP-32 events, organism-specific biosystem; G Protein Signaling Pathways, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Morphine addiction, organism-specific biosystem; Morphine addiction, conserved biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem;
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