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shRNA set against Rat NGFR (NM_012610.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH352136

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Gene Information

Cat. No. SHH352136
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr NGFR
Gene Name Ngfr nerve growth factor receptor (TNFR superfamily, member 16) [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Ngfr nerve growth factor receptor (TNFR superfamily, member 16) [ Mus musculus ]
Gene Symbol Ngfr
Synonyms p75; LNGFR; p75NTR; p75NGFR; Tnfrsf16
Gene Description nerve growth factor receptor (TNFR superfamily, member 16)
GeneID 18053
Uni ProtID Q8CFT3
mRNA Refseq NM_033217.3
Protein Refseq NP_150086.2
Chromosome Location 11 D; 11 55.6 cM
Function beta-amyloid binding; death receptor activity; nerve growth factor binding; nerve growth factor binding; neurotrophin TRKA receptor binding; neurotrophin binding; preprotein binding; protein binding; ubiquitin protein ligase binding;
Pathway Axonal growth inhibition (RHOA activation), organism-specific biosystem; Axonal growth stimulation, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Ceramide signalling, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; NADE modulates death signalling, organism-specific biosystem;
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