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Panoply™ Human NGFR Knockdown Stable Cell Line

Cat.No.
CSC-DC010361
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
NGFR
Synonyms
CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR
Gene ID
UniProt ID
P08138
mRNA Refseq
Protein Refseq
Chromosome Location
17q21-q22
Function
death receptor activity; nerve growth factor binding; protein binding; receptor activity; signal transducer activity; transmembrane signaling receptor activity; ubiquitin protein ligase binding;
Pathway
Axonal growth inhibition (RHOA activation), organism-specific biosystem; Axonal growth stimulation, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Ceramide signalling, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; NADE modulates death signalling, organism-specific biosystem;
MIM

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