shRNA set against Rat COMT (NM_012531.2)

Name: shRNA set against Rat COMT (NM_012531.2)
SKU: SHH267697
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH267697

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Gene Information

Cat. No.	SHH267697
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	COMT
Gene Name	Comt catechol-O-methyltransferase [ Mus musculus ]
Species	Rat
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Comt catechol-O-methyltransferase [ Mus musculus ]
Gene Symbol	Comt
Synonyms	Comt1; D16Wsu103e; D330014B15Rik
Gene Description	catechol-O-methyltransferase
Gene ID	12846
Uni Prot ID	O88587
m RNA Refseq	NM_007744.3
Protein Refseq	NP_031770.2
Chromosome Location	16 A3; 16 11.2 cM
Function	O-methyltransferase activity; catechol O-methyltransferase activity; catechol O-methyltransferase activity; catechol O-methyltransferase activity; magnesium ion binding; metal ion binding; methyltransferase activity; transferase activity;
Pathway	Biogenic Amine Synthesis, organism-specific biosystem; Biological oxidations, organism-specific biosystem; Dopamine clearance from the synaptic cleft, organism-specific biosystem; Dopaminergic synapse, organism-specific biosystem; Dopaminergic synapse, conserved biosystem; Enzymatic degradation of Dopamine by monoamine oxidase, organism-specific biosystem; Enzymatic degradation of dopamine by COMT, organism-specific biosystem;

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